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目的:了解引起过敏性休克药物的种类、频度及其它因素.方法:通过对公开发行的中文医药期刊及文献资料收集得到的药物致过敏性休克194例进行统计和分析。结果:最易引起过敏性休克的药物为抗生素类,占62例,其次为中药制剂和生物制剂,各占20例;出现频率较高的首推低分子右旋糖酐15例及庆大霉素11例;过敏性休克致死共30例.此外,给药途径、多种药物并用、连续长期用药、过敏体质及用药失误等也表明是致过敏性休克的重要因素.
OBJECTIVE: To understand the types, frequency and other factors of anaphylactic shock.Methods: Ninety-four cases of anaphylactic shock were collected and analyzed by the Chinese medicine journals and literature collected from the public. Results: The most easily induced anaphylactic shock drugs for the class of antibiotics, accounting for 62 cases, followed by traditional Chinese medicine preparation and biological agents, each of 20 cases; the higher the frequency of devaluation of low molecular dextran in 15 cases and gentamicin in 11 cases ; 30 cases of lethality due to anaphylactic shock. In addition, the administration route, combination of multiple drugs, continuous long-term medication, allergy and medication errors also indicate that it is an important factor in anaphylactic shock.