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目的 为了解发热出疹性疾病 (RFls)血清流行病学特征 ,以便更好地开展麻疹监测。方法 1998～2 0 0 1年 ,在铜陵市采集了爆发和散发病例的急性期血清标本 ,用酶联免疫吸附试验 (ELISA)捕捉法检测麻疹和风疹IgM抗体。结果 74例中麻疹IgM抗体阳性 15例 (2 0 .2 7% ) ;风疹IgM抗体阳性 15例 (2 0 .2 7% )。RFls病例的发病高峰为春夏季 ;15例麻疹IgM抗体阳性病例中 ,有免疫接种史者占 6 0 .0 0 % (9/ 15 ) ,免疫史不详和无免疫史者占 4 0 % (6 / 15 )。结论 血清学诊断是科学鉴别RFls的重要手段 ;加强麻疹疫苗的有效接种和强化免疫 ,积极推行风疹疫苗接种是控制麻疹和风疹发病的主要策略
Objectives To understand the epidemiological characteristics of fever and rash disease (RFls) in order to better monitor measles. Methods From 1998 to 2001, the acute phase serum samples were collected from Tongling City for detection and detection of measles and rubella IgM by enzyme-linked immunosorbent assay (ELISA). Results Among the 74 cases, 15 were measles IgM antibody positive (20.27%), 15 were rubella IgM positive (20.27%). The peak incidence of RFls cases was in spring and summer. Among the 15 cases of measles IgM antibody positive cases, 60% (9/15) had immunization history, 40% (40%) had unknown immunization history and no immunization history / 15). Conclusions Serological diagnosis is an important means of scientific identification of RFls. To strengthen measles vaccination and intensive immunization and to promote rubella vaccination is the main strategy to control the incidence of measles and rubella