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有关各类前列腺素(PGs)对雄性大鼠血浆中睾酮、LH、FSH的影响,已有一些学者作过报导,但结果很不一致。为了进一步搞清这一问题,作者进行了这一研究工作,以观察PGs处理之后,对睾丸、附睾、前列腺、精囊的重量、睾丸的胆固醇和抗坏血酸、前列腺酸性磷酸酶活性以及血浆中睾酮、LH、FSH的影响程度。作者将28只雄性成年大鼠(证明有生育能力的,体重在250～300g之间)均分为四组:第一组为对照组,每只鼠注射无菌生理盐水0.5ml/次;第二组每只鼠注射PGA-1 150μg/次;第三组每只鼠注射PGE-2 150μg/次;第四组每只鼠注射PGF-2α150μg/次。以上各组动物均作腹腔注射,每日两次(06:00和18:00),共注射10天。各种PG以乙
The effect of various types of prostaglandins (PGs) on testosterone, LH and FSH in male rats has been reported by some scholars, but the results are very different. To further clarify this issue, the authors conducted this study to observe the weight of testis, epididymis, prostate, seminal vesicle, testicular cholesterol and ascorbate, prostatic acid phosphatase activity, and plasma testosterone, LH , The impact of FSH. The authors divided 28 male adult rats (proven fertility, weighing 250-300g) into four groups: the first group was the control group, each injected with sterile saline 0.5ml / time; Each group in the two groups received PGA-1 150 μg / second; each group in the third group received PGE-2 150 μg / dose; in the fourth group, each group received PGF-2α 150 μg / dose. The above groups of animals were given intraperitoneal injections twice a day (06:00 and 18:00) for a total of 10 days. Various PG to B