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[目的] 分析温州市瓯海区2008—2013年预防接种后过敏性皮疹的发生特征. [方法] 收集温州市瓯海区2008—2013年疑似预防接种异常反应( AEFI)信息管理系统中诊断为过敏性皮疹的个案数据,采用描述性流行病学方法进行分析. [结果] 瓯海区2008—2013 年共报告过敏性皮疹111 例,过敏性皮疹报告发生率为3.58/10万剂. 男女性别比为1.27:1;<1岁儿童占65.77%;不伴发热的占75.68%;第三季度报告数占41.44%;主要发生在接种疫苗后24 h内(81.08%). 报告病例数居前三位的是麻-风疫苗(35.14%)、无细胞百白破疫苗(18.92%)、甲型H1N1流感疫苗(5.41%);报告发生率居前三位的是7价肺炎疫苗(115.85/10 万剂)、麻-风疫苗(29.33/10万剂)和甲型H1N1流感疫苗(13.07/10万剂). [结论] 需加强过敏性皮疹的鉴别诊断,虽然大部分疫苗过敏性皮疹报告发生率均在预期范围内,但仍需加强监测分析,尤其要关注发生率相对较高的疫苗.“,”[ Objective ] To analyze the characteristics of anaphylactic rash after vaccination in Ouhai District of Wenzhou City during 2008-2013. [ Methods ] Data on anaphylactic rash cases reported during 2008-2013 were collected through the national AEFI information management system.And descriptive epidemiologic methodology was used in this study. [ Results] A total of 111 anaphylactic rash cases were reported in Ouhai District during 2008-2013,the reported incidence rate of anaphylactic rash were 3.58 per million doses.The ratio of male-female was 1.27:1.Cases of ≤1 year old accounted for 65.77%.Those without fever accounted for 75.68%.The number of the reports for the third quarter of the year accounted for 41.44%of the total.The cases of anaphylactic rash mostly occurred within 24 h after immunization(81.08%) .The top three vaccines reported in occurrence of rash were measles and rubella at-tenuated live vaccine(35.14%), diphtheria, tetanus and acellular pertussis combined vaccine(18.92%), and A(H1N1)influenza vaccine(5.41%).The reported rates for the top three vaccines were 115.85, 29.33,13.07 per million doses for 7-valent pneumococcal polysaccharide conjugate vaccine,measles and rubella combined attenuated live vaccine, A(H1N1) influenza vaccine,respectively. [Conclusion] Differential diagnosis of anaphylactic rashes needs to be more stressed.Most anaphylactic rash were reported in the expected range,but still monitoring analysis on incidence of allergic rash should be enhanced.Vac-cines with higher incidence of rash reported should be further studied and analyzed.