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肿瘤细胞转移意味着肿瘤恶性程度增加,大部分肿瘤患者在临床确诊时已存在肿瘤转移,常规治疗死亡率极高。而一旦诊断为肿瘤,由于不能确定其是否转移,往往会接受过度治疗。因此,有关肿瘤细胞转移活性检测是肿瘤治疗的重要内容。良性肿瘤发展为转移性肿瘤至少包括四个相互关联的过程:①肿瘤细胞表面黏附分子减少,肿瘤间黏附能力下降。②原细胞间基质分解,并在肿瘤细胞诱导下重建适宜肿瘤生长的基质。③肿瘤细胞变形并生长出伪足,通过血
Tumor cell metastasis means that the degree of tumor malignancy increased, most of the tumor patients already have metastases in clinical diagnosis, the mortality rate of conventional treatment is extremely high. Once a tumor is diagnosed, over-treatment is often accepted because it can not be determined if it is metastasized. Therefore, the detection of tumor cell metastasis activity is an important part of cancer treatment. The development of benign tumors to metastatic tumors include at least four interrelated processes: ① reduced adhesion molecules on the surface of tumor cells, adhesion between tumors decreased. ② Proto-matrix stromal breakdown, and tumor cells in the induction of tumor cells to reconstruct the appropriate matrix. ③ tumor cell deformation and growth of pseudopodia, through the blood