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目的探讨亚甲蓝检测cN0期喉癌及下咽癌前哨淋巴结的价值。方法选择喉癌、下咽癌患者44例。术中全麻下注射亚甲蓝,检查蓝染的前哨淋巴结。前哨淋巴结全部切除后行肿瘤切除加选择性颈淋巴结清扫术,所有淋巴结送常规病理检查。结果 44例中,检出前哨淋巴结37例(84.1%)。以常规病理结果为金标准,淋巴结转移率为25.0%。前哨淋巴结敏感度81.8%,准确率95.5%,假阴性18.1%。结论亚甲蓝示踪法能有效地对cN0期喉癌及下咽癌进行前哨淋巴结定位,具有可操作性和实用性,可为减少手术创伤、提高患者生存质量提供依据。
Objective To investigate the value of methylene blue in detecting cN0 laryngeal cancer and sentinel lymph node in hypopharyngeal cancer. Methods Select 44 cases of laryngeal and hypopharyngeal cancer patients. Intraoperative anesthesia injection of methylene blue, check the blue dye sentinel lymph nodes. Sentinel lymph node resection combined with tumor resection plus selective cervical lymph node dissection, all lymph nodes to send routine pathological examination. Results Among the 44 cases, 37 cases (84.1%) of sentinel lymph nodes were detected. With routine pathological results as the gold standard, the lymph node metastasis rate was 25.0%. Sentinel lymph node sensitivity was 81.8%, accuracy 95.5%, false negative 18.1%. Conclusions Methylene blue tracer method can effectively locate sentinel lymph nodes in cN0 stage laryngeal carcinoma and hypopharyngeal carcinoma. It is feasible and practicable to provide the basis for reducing the trauma and improving the quality of life of patients.