【摘 要】
：
The proportions of patients with hepatocellular carcinoma (HCC) involving portal vein tumor thrombus (PVTT) varies greatly in different countries or regions, ranging from 13％ to 45％. The treatment regimens for PVTT recommended by HCC guidelines in differe
【机 构】
：
Hepatobiliary Surgery Department,Guangxi Liver Cancer Diagnosis and Treatment Engineering and Techno
论文部分内容阅读
The proportions of patients with hepatocellular carcinoma (HCC) involving portal vein tumor thrombus (PVTT) varies greatly in different countries or regions, ranging from 13％ to 45％. The treatment regimens for PVTT recommended by HCC guidelines in different countries or regions also vary greatly. In recent years, with the progress and development of surgical concepts, radiotherapy techniques, systematic therapies (for example, VEGF inhibitors, tyrosine kinase in-hibitors and immune checkpoint inhibitors), patients with HCC involving PVTT have more treatment options and their prognoses have been significantly improved. To achieve the maximum benefit, both clinicians and patients need to think rationally about the indications of treatment modalities, the occurrence of severe adverse events, and the optimal fit for the population. In this review, we provide an update on the treatment modalities available for patients with HCC in-volving PVTT. Trials with large sample size for patients with advanced or unresectable HCC are also reviewed.
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