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目的探讨百草枯中毒的预后和合理的治疗及护理方法。方法对我院重症监护病房40例口服百草枯中毒患者的临床资料进行回顾性分析。结果百草枯中毒患者血、尿毒物浓度是影响预后的重要因素。合理的综合治疗和护理能使部分口服致死量患者存活。给予早期洗胃、有效导泻、血液净化的序贯应用、早期应用抗氧化损伤药物和肾上腺皮质激素可降低病死率;死亡组死因多为多脏器功能衰竭(MOF)及急性呼吸窘迫综合征(ARDS)。结论对百草枯中毒患者进行院前、急诊科及院内一体化救治,以及良好的综合治疗和护理可以提高患者的生存。
Objective To investigate the prognosis of paraquat poisoning and rational treatment and nursing methods. Methods The clinical data of 40 patients with paraquat poisoning in our intensive care unit were retrospectively analyzed. Results Paraquat poisoning in patients with blood, urine toxin concentration is an important factor affecting the prognosis. Reasonable comprehensive treatment and care can make some oral lethality patients survive. Early gastric lavage, effective cathartic and blood purification sequential administration, early application of anti-oxidative damage drugs and adrenal cortex hormones can reduce the mortality rate; the death of the cause of death were mostly multiple organ failure (MOF) and acute respiratory distress syndrome (ARDS). Conclusion Paraquat poisoning in patients with prehospital, emergency department and hospital integrated treatment, and good comprehensive treatment and care can improve patient survival.