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报告1例丛状栅栏状有包膜神经瘤.患者男,42岁.右口角外侧丘疹8年.皮肤科检查:有口角外侧一肤色丘疹,质中,表面光滑.皮损组织病理:真皮内可见多个肿瘤团块,境界清楚,瘤团内梭形细胞增生,其间可见较多裂隙,瘤团外层细胞呈栅栏状排列,细胞异形性不明显.免疫病理:增生的梭形瘤细胞S-100蛋白阳性,肿瘤细胞间可见散在神经纤维丝蛋白(NFPR)阳性的神经轴突,肿瘤周围可见上皮膜抗原(EMA)弱阳性的不完整的包膜.诊断:丛状栅栏状有包膜神经瘤.“,”A 42-year-old man presented with an eruption on his face for 8 years.Physical examination revealed a well-demarcated,smooth skin-colored papule with moderate hardness on his face.The lesion was asymptomatic and gradually increased in size.Histopathology showed multiple well-circumscribed nodules composed of intersecting fascicles of the spindle cells which were separated by characteristic clefts in the dermis.Immunohistochemical staining revealed that tumor cells werc diffusively positive for S-100,along with scattered axons with NFPR positive.Surrounding the tumor were incomplete capsules stained weakly positive for EMA.Based on the above histopathological and immunohistochemical findings,a diagnosis of plcxiform palisaded encapsulated neuroma was made.