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目的观察肺泡灌洗在重症肺炎的疗效。方法69例重症肺炎患者随机分为灌洗组和非灌洗(对照)组。对照组采用常规治疗;灌洗组加用支气管肺泡灌洗。记录灌洗前24 h及之后24、48和72 h时急性生理学和慢性健康状况Ⅱ(APACHEⅡ)评分、急性肺损伤评分和肺感染评分。结果与对照组相比,灌洗组肺泡灌洗之后各项评分均有不同程度的下降,其中48～72 h三种评分结果明显低于对照组(P<0.01)。结论支气管肺泡灌洗能降低肺部炎症,减轻肺损伤,对重症肺炎有明显的治疗作用。
Objective To observe the efficacy of alveolar lavage in severe pneumonia. Methods 69 patients with severe pneumonia were randomly divided into lavage group and non-lavage (control group). The control group with conventional treatment; lavage group plus bronchoalveolar lavage. The acute physiology and chronic health status Ⅱ (APACHEⅡ) score, acute lung injury score and lung infection score at 24 h, 48 h and 72 h after lavage were recorded. Results Compared with the control group, the score of alveolar lavage in the lavage group decreased to some extent, among which the scores of 48 ~ 72 h were significantly lower than those of the control group (P <0.01). Conclusion Bronchoalveolar lavage can reduce lung inflammation, reduce lung injury, and have significant therapeutic effect on severe pneumonia.