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本实验研究采用D-半乳糖衰老模型小鼠，灌胃熟地黄水提液30d，测定脑Na+、K+－ATPase活性和MDA含量．结果表明，与衰老模型组比较，熟地黄水提液能显著提高小鼠红细胞膜Na+、K+－ATPase活性，显著降低MDA含量（P<0．01）．
In this experiment, D-galactose aging mice were used to administer the extract of Radix Rehmanniae Preparata for 30 days. The activity of Na+, K+-ATPase and MDA in the brain were measured. The results showed that compared with the aging model group, Rehmannia glutinosa extract could significantly increase Na+, K+-ATPase activity of erythrocyte membrane and significantly reduce MDA content (P<0.01).