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We report an experimental study of electron transport properties of MnSe/(Bi,Sb)2Te3 heterostructures,in which MnSe is an antiferromagnetic insulator,and (Bi,Sb)2Te3 is a three-dimensional topological insulator (TI).Strong magnetic proximity effect is manifested in the measurements of the Hall effect and longitudinal resistances.Our analysis shows that the gate voltage can substantially modify the anomalous Hall conductance,which exceeds 0.1e2/h at temperature T =1.6K and magnetic field μ0H =5T,even though only the top TI surface is in proximity to MnSe.This work suggests that heterostructures based on antiferromagnetic insulators provide a promising platform for investigating a wide range of topological spintronic phenomena.