论文部分内容阅读
有效地预防与控制G~-菌感染、内毒素休克是提高临床危重病人救治率的关键。大量的动物实验证明:内毒素核心糖脂(CGL)抗体(包括抗血清及单克隆抗体)对同源或异源G~-菌及其内毒素的攻击具有良好的保护作用。临床初步应用亦显示出较好的疗效。但对此仍有不同的看法,其确切的作用机理尚待阐明。CGL单克隆抗体的研究和推广应用可能成为临床防治内毒素血症及其严重并发症的有效途径。
Effective prevention and control of G ~ - bacterial infection, endotoxic shock is to improve the critical rate of treatment of critically ill patients. A large number of animal experiments show that endotoxin CGL antibodies (including antisera and monoclonal antibodies) have a good protective effect against homologous or heterologous G ~ - bacteria and endotoxin attack. Preliminary clinical application also shows good effect. However, there is still a different view on this, and its exact mechanism of action remains to be elucidated. The research and popularization and application of CGL monoclonal antibody may become an effective way for clinical prevention and treatment of endotoxemia and its serious complications.