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本文旨在研究睾酮水平升高时两种结合蛋白系统(白蛋白和球蛋白)的不同变化,并考察非特异性结合睾酮,即白蛋白结合睾酮和游离睾酮是否可作为雄激素过多症的有用指标. 受试者分为三组:(1)月经正常无多毛组(NC)17人;(2)月经正常伴多毛组(HR)20人;(3)多毛伴稀发月经或闭经组(HO/A)20人.每人单次抽血测血清总睾酮(T)、性激素结合蛋白(SHBG)、白蛋白及非SHBG结合睾酮.血清总睾酮用I~(125)睾酮药盒测定.SHBG结合容
This article aims to investigate the different changes in the two binding protein systems (albumin and globulin) with elevated testosterone levels and investigate whether nonspecific binding of testosterone, ie albumin-bound testosterone and free testosterone, may be useful as androgen hyperaccumulation The subjects were divided into three groups: (1) normal menstrual hairless group (NC) 17; (2) normal menstruation with hairy group (HR) 20; (3) hairy with thinning menses or amenorrhea group HO / A), and the total testosterone (T), sex hormone binding protein (SHBG), albumin and non-SHBG combined with testosterone were measured by single blood test per person, and total testosterone in serum was measured with I 125 testosterone kit. SHBG binding capacity