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本文分析187例经131I治疗的Graves病患者血清TT3、TT4变化值,结果表明TT3差值和比值、TT4差值和比值都能够反映131I治疗后甲状腺所受电离辐射破坏的程度,表现为131I治疗后未愈组、甲低级和治愈组的差值、比值间差异有统计学意义(p<0.001)。并寻找出预测131I治疗未愈或甲低的判断标准,其判断预后的特异度分别为94.6%和94.8%、准确率为89.3%和93.1%、灵敏度为85.8%和84.4%,从而提示用此标准能够在131I治疗3~6个月作出预后的预测。
In this paper, 187 cases of 131I treatment of Graves disease serum TT3, TT4 changes in the results showed that TT3 difference and ratio, TT4 difference and ratio can reflect the degree of 131I treatment of thyroid damage by ionizing radiation, the performance of 131I treatment There was significant difference (P <0.001) between difference and ratio of post-treatment, post-treatment and post-treatment. And to find out the predictive criteria for 131I treatment of unhealed or hypothyroidism, the specificity of the prognosis was 94.6% and 94.8% respectively, the accuracy rates were 89.3% and 93.1% respectively, and the sensitivity was 85%. 8% and 84.4%, suggesting that using this standard can predict prognosis in 131I treatment of 3 to 6 months.