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小柴胡汤方剂出自张仲景的《伤寒杂病论》,由柴胡、黄芩、人参(现多以党参代之)、甘草(炙)、生姜、半夏、大枣7味中药组成,主要用于少阳证的治疗,具有较好的临床效果。我们将传统汤剂改成口服液,并应用 L_8(2~7)正交试验表进行试验,确定了口服液的最佳工艺。1 实验部分1.1 实验仪器与材料恒温水浴箱,25型pH 计;柴胡、黄芩、党参、甘草(炙)、半夏(购于南昌市药材公司)、生姜、大枣(自购)。1.2 基本工艺拟定根据口服液生产实践经验,拟定其基本工艺流程如下:(1)收集蒸
The Xiaochaihu Decoction consists of Zhang Zhongjing’s “Treatise on Febrile and Miscellaneous Diseases”. It consists of four herbs, namely Bupleurum, Astragalus membranaceus, Ginseng (now mostly substituted with Codonopsis pilosula), licorice root, ginger, Pinellia, and jujube. Shaoyang card treatment has a good clinical effect. We changed the traditional decoction into an oral solution and applied the L_8 (2~7) orthogonal test table to test and determined the optimal process for the oral solution. 1 Experimental section 1.1 Experimental equipment and materials Constant temperature water bath, type 25 pH meter; Bupleurum, Radix Astragali, Radix Codonopsis, Glycyrrhiza glabra, Pinellia (purchased from Nanchang Medicinal Materials Company), ginger, jujube (purchase). 1.2 Basic Process Formulation Based on oral liquid production practice experience, the basic process flow is formulated as follows: (1) Collect steam