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研究了四种北柴胡提取物对小鼠体内外免疫功能的影响。结果：柴胡水溶部分及药渣水煎剂对小鼠Ｔ、Ｂ淋巴细胞均有刺激增生作用，４０％醇提物能促进Ｂ淋巴细胞的增殖，正丁醇提物则对Ｔ淋巴细胞增殖有增强效应。四种提取物均能增强巨噬细胞吞噬功能，但对抗体形成细胞无明显影响。研究还发现药渣水煎剂能刺激活化的Ｔ淋巴细胞分泌白细胞介素－２（ＩＬ－２），该结果可能是柴胡促进细胞免疫、抗肿瘤效应的机理之一。
The effects of four Bupleurum extract on immune function in vivo and in vitro were studied. Results: The water-soluble fraction of Bupleurum chinense and dregs decoction could stimulate the proliferation of T and B lymphocytes in mice. 40% ethanol extract could promote the proliferation of B lymphocytes, and n-butanol extract could promote the proliferation of T lymphocytes There are enhancements. All four extracts can enhance phagocytosis of macrophages, but have no significant effect on antibody-forming cells. The study also found that dregs decoction can stimulate activated T lymphocytes to secrete interleukin-2 (IL-2), the result may be Bupleurum promote cellular immunity, anti-tumor effect of one of the mechanisms.