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目的观察索利那新治疗输尿管镜碎石术后双J管相关症状的疗效。方法回顾性分析76例单侧输尿管中下段结石,并成功行输尿管镜碎石且术后留置双J管的患者。随机分为两组,治疗组(n=38)给予索利那新5mg,1次/d,口服2～3周;对照组(n=38)未给予干预治疗。所有患者在置管2～3周后均随访并完成输尿管支架管相关症状问卷。结果治疗组排尿症状、躯体疼痛症状、身体一般状况、工作能力情况、性生活情况平均评分低于对照组,治疗组均较对照组有明显改善(P<0.05)。结论索利那新能有效改善对留置双J管患者的症状及生活质量。
Objective To observe the efficacy of solifenacin in treating double J-tube related symptoms after ureteroscopic lithotripsy. Methods A retrospective analysis of 76 cases of unilateral ureteral calculi, and the success of ureteroscopic lithotripsy and double-J tube after the surgery. The patients in the treatment group (n = 38) were given solifenacin 5 mg once daily for 2 to 3 weeks. The control group (n = 38) was given no intervention. All patients were followed up 2 to 3 weeks after catheterization and completed the ureteral stent-related symptoms questionnaire. Results The urinary symptoms, physical pain symptoms, general physical condition, working ability and sexual life condition in the treatment group were lower than those in the control group. The treatment group was significantly improved compared with the control group (P <0.05). Conclusion Solifenacin can effectively improve the symptoms and quality of life in patients with double J tube.