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目的:观察针刺加肌氨肽苷治疗缺血性脑卒中认知功能障碍的临床疗效。方法:选择缺血性脑卒中认知功能障碍240例,随机分为观察组和对照组各120例。对照组采用肌氨肽苷注射液治疗,每次7mg,加入5%葡萄糖或0.9%氯化钠注射液250ml中静脉滴注,每天1次。观察组在对照组治疗的基础上,增加印堂、上星、内关、人中、太阳、足三里、风池、百会针刺治疗。均治疗21天,观察两组临床症状和神经功能改善情况。结果:观察组临床总有效118例(98.3%),对照组80例(66.7%);两组比较,差异非常显著(P<0.01)。观察组与对照组治疗后神经功能缺损评分分别为(6.05±4.95)分和(8.46±7.36)分;两组比较,差异非常显著(P<0.01)。结论:针刺加肌氨肽苷治疗缺血性脑卒中认知功能障碍临床疗效优于单纯肌氨肽苷注射液治疗。
Objective: To observe the clinical effect of acupuncture combined with aminoglycoside on cognitive dysfunction in ischemic stroke. Methods: A total of 240 cognitive dysfunction patients with ischemic stroke were randomly divided into observation group (120 cases) and control group (120 cases). The control group with muscle aminopeptidase injection for treatment, each 7mg, adding 5% glucose or 0.9% sodium chloride injection 250ml intravenous infusion, once daily. Observation group in the control group based on the treatment, an increase of Yintang, on the star, the customs, people, the sun, Zusanli, Fengchi, Baihui acupuncture treatment. After 21 days of treatment, the clinical symptoms and neurological function were observed in both groups. Results: The total clinical effective rate was 118 (98.3%) in the observation group and 80 (66.7%) in the control group. The difference between the two groups was significant (P <0.01). The scores of neurological deficits in the observation group and the control group after treatment were (6.05 ± 4.95) and (8.46 ± 7.36) points respectively. The differences between the two groups were significant (P <0.01). Conclusion: The clinical effects of acupuncture combined with aminoglycoside in the treatment of cognitive dysfunction in ischemic stroke are better than that of simple amisperidin injection.