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目的研究全反式维甲酸(维甲酸)治疗难治性ITP的方法。方法回顾性分析我院使用维甲酸治疗难治性ITP3例患者资料,总结维甲酸治疗难治性ITP的方法。结果根据疗效判定标准,前两例均属良效,第3例因不能耐受,故不能做判定。从第2例看,停维甲酸后PLT下降,恢复服药后PLT上升,说明维甲酸治疗难治性ITP确实有效。结论维甲酸价格便宜毒副作用小,只需口服不必住院,对基层医院来说值得推广。
Objective To study the treatment of refractory ITP with all-trans retinoic acid (retinoic acid). Methods Retrospective analysis of the use of retinoic acid in our hospital in patients with refractory ITP3 data, summarize the method of Tretinoin treatment of refractory ITP. Results According to the efficacy criteria, the first two cases are good, the third case can not tolerate, it can not make a decision. From the second case, PLT decreased after stopping of retinoid acid, PLT recovery after treatment increased, indicating that retinoic acid treatment of refractory ITP is indeed effective. Conclusion The price of retinoic acid is cheap and the toxic side effects are small. Oral administration does not have to be hospitalized, which is worthy of promotion for primary hospitals.