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卵巢恶性肿瘤的早期诊断及治疗一直是妇科肿瘤关注的重点。巨噬细胞集落刺激因子(M-CSF)是近年来受到广泛重视的具有多种生物学功能的细胞因子,尤其在肿瘤的发生、发展方面越来越受到关注。最近研究发现,上皮性卵巢癌患者血清中存在M-CSF的异常表达,因此,探讨卵巢恶性肿瘤与M-CSF的关系对于卵巢恶性肿瘤的早期诊断有着极其重要的意义。
Early diagnosis and treatment of ovarian cancer has been the focus of gynecologic oncology. Macrophage colony-stimulating factor (M-CSF) is a cytokine with many biological functions, which has been widely paid attention in recent years. It is attracting more and more attention especially in tumorigenesis and development. Recent studies have found that abnormal expression of M-CSF exists in the serum of patients with epithelial ovarian cancer. Therefore, to explore the relationship between ovarian cancer and M-CSF is of great significance for the early diagnosis of ovarian cancer.