Clinical characteristics and ABCC2 genotype in Dubin-Johnson syndrome:A case report and review of th

• 作 者: Huan Wu Xue-Ke Zhao Juan-Juan
• 机 构: DepartmentofInfectiousDiseases
• 出 处: 世界临床病例杂志
• 发表日期: 2021年4期
• 关键词: Dubin-Johnson syndrome ABCC2 genotype Next-generation sequencing ABCC2 mutation
• 基金项目: Supported by The Talents of Qiankehe platform of China,No.[2018]5779-40,the Zhuke Contract,No.[2018]1-92,and the Qiankehe Support,No.[2017]2874.

BACKGROUND Dubin-Johnson syndrome(DJS)is a benign autosomal recessive liver disease involving mutations of the ABCC2 gene.It is characterized by chronic or intermittent conjugated hyperbilirubinemia,with chronic idiopathic jaundice as the main clinical ma