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肾素-血管紧张素系统(RAS)在血压调节和高血压发病中具有重要作用。而RAS本身也受到中枢神经系统的调制及多种体液因素的影响。研究证明脑内存在有血管紧张素Ⅱ受体(ANGⅡR)激活ANGⅡ可以引起血压升高等一系列变化。在肾性高血压大鼠我们曾观察到中枢和外周的环核苷酸浓度的
The renin-angiotensin system (RAS) plays an important role in the regulation of blood pressure and the pathogenesis of hypertension. The RAS itself is also affected by the modulation of the central nervous system and a variety of body fluids. Studies have shown that there is a brain angiotensin Ⅱ receptor (ANG Ⅱ R) to activate ANG Ⅱ can cause a series of changes such as blood pressure. We have observed central and peripheral concentrations of cyclic nucleotides in renal hypertensive rats