论文部分内容阅读
近来的研究已证明,对于常用的化学疗法无效的急性白血病患者,给于大剂量的阿糖胞苷治疗则能奏效。但某些患者在接受阿糖胞苷治疗中发生过眼结膜与角膜的毒性症状。这种不良作用的发生率及严重程度与药物的曝光时间的关系尚不清楚。我们最近曾治疗了一例顽固性的髓性白血病,据此,可提出其间的关系。
Recent studies have demonstrated that treatment with high doses of cytarabine can be effective in patients with acute leukemia who are refractory to commonly used chemotherapy. However, some patients experience ocular conjunctival and corneal toxicities during cytarabine treatment. The relationship between the incidence and severity of this adverse effect and the exposure time to the drug is not clear. We have recently treated a case of intractable myeloid leukemias, from which we can suggest the relationship.