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目的了解入伍新兵人群中Y群流脑IgG抗体的流行分布情况,为今后预防提供科学依据。方法采用血清流行病学调查方法,利用酶联免疫吸附试验(ELISA)技术,对北京军区近4年来自7个省市的360名入伍新兵血清进行了Y群流脑IgG抗体检测,统计分析其阳性率。结果发现各年间入伍新兵血清Y群流脑IgG抗体历年间无显著变化,为28.57%~60.78%,平均43.61%;抗体含量,为0.000~98.622μg/ml,平均4.590μg/ml;地区间差别显著,内蒙古(60.78%)、陕西省(55.00%)和湖北省(48.33%)较高,山东省(28.57%)和北京市(33.33%)较低;入伍前工作与否,抗体阳性检出率无显著性差别;其差别的主要原因可能与各地区隐性感染和时间长短有关。结论入伍新兵人群中Y群流脑IgG抗体阳性率为28.57%~60.78%,抗体平均含量,为4.590μg/ml,并有显著性地区差异;所以,在新兵入伍期间,采取预防接种、健康教育等有效预防措施。
Objective To understand the epidemiological distribution of Y group migratory brain IgG antibodies in recruits recruits, providing a scientific basis for future prevention. Methods Using serological epidemiological survey method, ELISA of Y group was used to detect the IgM serogroup Y IgG of 360 enlisted recruits in Beijing Military Region in recent 4 years from 7 provinces and cities. Statistical analysis was performed Positive rate. The results showed that there was no significant change in serogroup Y antibody of serogroup Y in recruits from year to year, ranging from 28.57% to 60.78% with an average of 43.61%; antibody content was from 0.000 to 98.622μg / ml with an average of 4.590μg / ml; Significantly, Inner Mongolia (60.78%), Shaanxi Province (55.00%) and Hubei Province (48.33%) were higher than those in Shandong Province (28.57%) and Beijing (33.33%). No significant difference in rates; the main reason for the difference may be related to the duration of latent infection and the length of the region. Conclusions The positive rate of IgM IgG in group Y recruits is 28.57% -60.78% and the average level of antibody is 4.590μg / ml, and there are significant regional differences. Therefore, during recruits recruitment, vaccination and health education And other effective preventive measures.