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东海大学医学部生化科的胜沼恒彦教授等的研究小组,从大白鼠粪便中发现了食欲控制物质,这种物质称为FS-T,是肠内细菌所产生的多糖的一种。在以大白鼠为对象,研究FS-T活性时,发现投药后2个小时达高峰,食欲抑制率达50%。如果大量生产食欲抑制物,除治疗过食症之外,还可能成为控制肥胖剂。为此,该研究所今后将对产生这种物质的细菌种类、这种物质的性质、生产方法等进行研究。
The research team of Prof. Shinmaki Mama and others from Biochemical Section, Biochemistry Department, Department of Biochemistry, Tokai University found appetite control substance from rat feces. This substance is called FS-T and is one kind of polysaccharide produced by intestinal bacteria. In the study of FS-T activity in rats, the peak was reached at 2 hours after administration and the appetite suppression rate was 50%. If mass production of appetite suppressants, in addition to the treatment of over-eating disorders, but also may become a control obesity agent. To this end, the Institute will in future produce the species of bacteria, the nature of the material, production methods and so on.