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目的:探讨吲达帕胺联合氨氯地平治疗高血压合并冠心病的药学特点。方法:选取2012年4月-2015年5月我院收治入院的120例高血压合并冠心病患者,随机分成两组,每组60例,观察组采用吲达帕胺+氨氯地平进行治疗,对照组采用硝苯地平控释片+硝酸甘油片进行治疗,观察两组治疗效果,分析药学特点。结果:观察组治疗总有效率明显高于对照组,P<0.05,有统计学意义。结论:吲达帕胺联合氨氯地平治疗高血压合并冠心病药学效果显著,值得临床推广。
Objective: To investigate the pharmacokinetics of indapamide combined with amlodipine in the treatment of hypertension and coronary heart disease. Methods: From April 2012 to May 2015, 120 patients with hypertension and coronary heart disease admitted to our hospital were randomly divided into two groups of 60 patients. The observation group was treated with indapamide + amlodipine, The control group was treated with nifedipine controlled release tablets and nitroglycerin tablets. The therapeutic effects were observed and the pharmacological characteristics were analyzed. Results: The total effective rate of observation group was significantly higher than that of control group, P <0.05, with statistical significance. Conclusion: Indapamide combined with amlodipine in the treatment of hypertension complicated by coronary heart disease has significant clinical effect and is worthy of clinical promotion.