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笔者强调了肾性骨营养不良的概念。叙述了肾性骨营养不良发生的相关因素,包括慢性肾脏病继发甲状旁腺功能亢进、金属中毒、局部细胞因子异常、代谢产物残留、生长和分化因子异常等,以及其发生的机理。叙述了肾性骨营养不良的分类:高转运骨病、低转运骨病以及混合型骨病。肾性骨营养不良的临床表现:骨痛、骨骼畸形、异位钙化、皮肤瘙痒和肌病等。诊断方法:影像学、骨活检及化验检查。进而还对其治疗方法进行了总结。
The author emphasizes the concept of renal osteodystrophy. The related factors of renal dystrophy were described, including secondary hyperparathyroidism of chronic kidney disease, metal poisoning, abnormalities of local cytokines, residues of metabolites, abnormal growth and differentiation factors, and their mechanism. Described the classification of renal osteodystrophy: high transfer of bone disease, low transfer of bone disease and mixed bone disease. Clinical manifestations of renal osteodystrophy: bone pain, skeletal deformities, ectopic calcification, skin itching and myopathy. Diagnostic methods: imaging, bone biopsy and laboratory tests. Then the treatment method is also summarized.