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目的探讨肾上腺节细胞神经瘤的诊断及鉴别诊断,提高对该病的诊治水平。方法回顾性分析12例肾上腺节细胞神经瘤患者的临床表现和超声、CT及MRI等影像学结果,并结合相关文献提高对该病的诊断和鉴别诊断。7例患者行后腹腔镜肾上腺肿物切除术,3例行开放性肾上腺肿物切除术,2例行单孔腹腔镜肾上腺肿物切除术,患者术前均按嗜铬细胞瘤准备。结果 12例患者中11例通过术前影像学检查诊断明确与术后病理一致,1例术前考虑嗜铬细胞瘤,术后病理结果为肾上腺节细胞神经瘤。12例均顺利完成手术,术中生命体征均未见明显异常。住院时间为9～17 d,平均13.2 d,术后随访1～5年,11例未见明显复发,1例失访。结论肾上腺节细胞神经瘤为临床上罕见的良性肿瘤,多无特异性临床表现。影像学检查是诊断本病的重要手段,也是与其他肾上腺疾病相鉴别的重要方法,但最终诊断仍以病理为主。
Objective To investigate the diagnosis and differential diagnosis of adrenal ganglion neuroma and improve the diagnosis and treatment of this disease. Methods The clinical manifestations of 12 patients with adrenal ganglioneuroma and the imaging findings of ultrasound, CT and MRI were retrospectively analyzed. The related literature was used to improve the diagnosis and differential diagnosis of the disease. Seven patients underwent laparoscopic adrenalectomy, 3 underwent open adrenalectomy, and 2 underwent single-hole laparoscopic adrenalectomy. All patients underwent preoperative pheochromocytoma preparation. Results Of the 12 patients, 11 were diagnosed with preoperative pathology by preoperative imaging examination. One patient considered pheochromocytoma before surgery. The postoperative pathological result was adrenal ganglion neuroma. All 12 cases completed the operation successfully, and no significant abnormalities were found in the vital signs during the operation. The hospitalization time was 9-17 days with an average of 13.2 days. After a follow-up of 1 to 5 years, no obvious recurrence was found in 11 cases and 1 case was lost to follow-up. Conclusion Adrenal ganglioneuromas are rare benign tumors in clinical practice. They have no specific clinical manifestations. Imaging examination is an important means of diagnosing this disease, and it is also an important method of distinguishing from other adrenal diseases, but the final diagnosis is still based on pathology.