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[目的]探讨上海宝山地区人群胃食管反流病(GERD)的患病率及发病危险因素。[方法]采用中文版反流性疾病问卷(RDQ),应用随机、整群、分层抽样方法对上海宝山地区≥18岁居民进行调查,调查方式为面试。[结果]实际调查3 126例(男1 635例,女1 491例),年龄18~87(43.5±17.1)岁;按RDQ评分≥12分定义,GERD的患病率为8.5%(266/3 126);30~<40岁人群GERD患病率与其他年龄比较,差异有统计学意义(P<0.05);男性患病率高于女性,但两性比较差异无统计学意义(P>0.05)。GERD组伴发口咽疾病、鼾症、哮喘的比例明显高于非GERD组,2组比较差异有统计学意义(P<0.05);饱食、便秘、吸烟是GERD患病的独立危险因素。GERD组SF-36量表8个维度生活质量评分和量表总评分均明显低于非GERD组,差异有统计学意义(P<0.05)。[结论]上海宝山地区GERD患病率略高于上海市水平,GERD患者生活质量较正常健康人群明显下降。
[Objective] To investigate the prevalence and risk factors of gastroesophageal reflux disease (GERD) in Shanghai Baoshan area. [Methods] The Chinese version of Reflux Disease Questionnaire (RDQ) was used to investigate the residents aged 18 or above in Baoshan district of Shanghai using randomized, cluster-based and stratified sampling methods. The survey method was interview. [Results] The actual survey was 3 126 cases (1 635 males and 1 491 females) aged 18-87 years (43.5 ± 17.1 years). According to the RDQ score ≥12, the prevalence of GERD was 8.5% (266 / The prevalence of GERD in 30 ~ 40-year-old population was significantly different from other age groups (P <0.05). The prevalence of GERD was higher in males than in females, but the difference was not statistically significant (P> 0.05 ). The rates of oral and pharyngeal diseases, snoring and asthma in GERD group were significantly higher than those in non-GERD group (P <0.05). Satiety, constipation and smoking were the independent risk factors of GERD. In the GERD group, the scores of quality of life and total scale of SF-36 in 8 dimensions were significantly lower than those in non-GERD group (P <0.05). [Conclusion] The prevalence of GERD in Shanghai Baoshan area is slightly higher than that in Shanghai. The quality of life of patients with GERD is obviously lower than that of normal healthy people.