Interaction between Bifunctional Dioxo Macrocyclic Polyamine Co(II) Complex and DNA in Metallomicell

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The cleavage of DNA (pUC18) by lipophilic macrocyclic polyamine Co(II) complex was investigated in metallomicellar system. The results showed that the conversion of plasmid DNA (pUC18) increases with the increase of the concentration of complex under physiological conditions.
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