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[目的]了解四川省儿童大骨节病病情现状及相关危险因素。[方法]调查74个大骨节病病区村的自然环境和社会经济等基础资料,采用临床和X线拍片的方法,调查儿童大骨节病病情现状,采集儿童发样及当地主食粮样进行含硒量检测。[结果]临床检查7～12岁儿童4530名,检出Ⅰ度患者8例,临床检出率为0.18%;拍摄7～12岁儿童右手X线片4530张,X线阳性片83张,阳性检出率平均为1.83%(0～13.73%),病情活跃程度指数平均为1.30,病情严重程度指数平均为1.83。儿童发硒水平平均为(0.26±0.07)mg/kg。粮食硒水平平均为(0.0067±0.0018)mg/kg,T2毒素含量平均为31.39ppb(2.67～101.14)。[结论]2009年四川省儿童大骨节病病情较为稳定,处于控制或基本控制范围,仅局部地区病情活跃,与主食种类及来源关系密切。
[Objective] To understand the current situation of Kashin-Beck disease in children in Sichuan Province and related risk factors. [Methods] The basic data such as natural environment and social economy of 74 Kashin-Beck disease villages were investigated. The clinical status and X-ray film were used to investigate the status of Kashin-Beck disease in children. Selenium detection. [Results] 4530 children aged 7-12 years were examined clinically. Among them, 8 cases with grade Ⅰ were detected and the clinical detection rate was 0.18%. 4530 right X-ray films and 83 positive X-ray films were obtained from children aged 7 to 12 The average detection rate was 1.83% (0 ~ 13.73%), the average severity of illness index was 1.30, the average severity index was 1.83. Selenium levels in children averaged (0.26 ± 0.07) mg / kg. The average level of selenium in grain was (0.0067 ± 0.0018) mg / kg, and the average content of T2 toxin was 31.39ppb (2.67 ~ 101.14). [Conclusion] The prevalence of Kashin-Beck disease in children in Sichuan Province was relatively stable in 2009, under the control or basic control. Only in some areas was the disease active and closely related to the types and sources of staple food.