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目的:研究分析氟喹诺酮类药物在结核病治疗中的临床应用。方法:随机选取我所自2008年5月至2014年9月间在我所进行治疗的60例结核病患者作为本次研究的对象,所选对象来我所就诊之前均有不规则的抗结核治疗史,后按照随机双盲法将其分为研究组30例,和对照组30例,对照组患者采用丙硫异烟肼+利福喷汀+力克肺疾+吡嗪酰胺治疗,而研究组的患者则在对照组的用药基础上采用氟喹诺酮类药物(左氧氟沙星)进行治疗。然后对比观察两组患者的临床治疗效果。结果:研究结果显示,研究组的临床治疗总有效率明显较对照组高,差异具有显著性,(P<0.05)具有统计学意义。结论:研究表明,氟喹诺酮类药物在结核病患者的治疗领域具有重要的应用价值,并且临床疗效较为显著。
Objective: To study the clinical application of fluoroquinolones in the treatment of tuberculosis. Methods: Sixty patients with tuberculosis who were treated in our hospital from May 2008 to September 2014 were randomly selected as the subjects of this study. The selected subjects had irregular antituberculosis treatment before I came to our clinic According to the randomized double-blind method, they were divided into study group 30 cases and control group 30 cases. Patients in the control group were treated with propylthiisothiazepine + rifapentine + Lectra pulmonary disease + pyrazinamide, and the study group Of patients in the control group based on the use of fluoroquinolones (levofloxacin) for treatment. Then compare the clinical efficacy of two groups of patients. Results: The results showed that the total effective rate of clinical treatment in study group was significantly higher than that in control group, with significant difference (P <0.05). Conclusion: The study shows that fluoroquinolones have important clinical value in the treatment of tuberculosis patients, and the clinical efficacy is more significant.