Culture and regulation of osteoblasts in multiple myeloma patients

• 作 者: 高珊
• 机 构: Dept Clin Hematol,General Hosp,Tianjin Med Univ,
• 出 处: China Medical Abstracts(Internal Medicine)
• 发表日期: 2014年02期
• 关键词: myeloma cultured cytometry enrolled osteo creased invitro

Objective To investigate the biological characteristics of osteoblasts cultured in vitro from bone marrow(BM)of multiple myeloma(MM)patients and to explore their generation and osteogenic potential.Effects of some factors such as bortezomib and MM patient serum on the osteoblasts were observed.Methods Twenty MM patients and 10 healthy donors as controls were enrolled in this study.Osteoblasts from MM patients’BM were cultured

Objective To investigate the biological characteristics of osteoblasts cultured in vitro from bone marrow (BM) of multiple myeloma (MM) patients and to explore their generation and osteogenic potential. Effects of some factors such as bortezomib and MM patient serum on the osteoblasts were observed. Methods Twenty MM patients and 10 healthy donors as controls were enrolled in this study. Osteoblasts from MM patients’BM were cultured