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新生儿呼吸暂停是新生儿期某些疾病引起的常见急症,常表示原发病的加重恶化。如及时合理的治疗,对预后十分重要。我院自1991～1996年共收治30例患儿,用东莨菪碱与氨茶碱治疗,疗效满意,现报道如下。 1.临床资料 一般资料:30例患儿中男18例,女12例,年龄≤5天15例,6～15天13例,16～28天2例。胎龄均在37～40周,出生时体重不足2500克的有5例。原发疾病:新生儿肺炎15例,新生儿颅内出血5例,新生儿败血症5例,新生儿低钙3例,新生儿硬肿症2例。呼吸暂停伴呼吸困难16例,伴惊厥22例。呼吸暂停最少发作3次,最多发作40余次。呼吸暂停持续时间最长达50小时。 诊断标准:(1)呼吸停止20秒钟以下伴有心率减慢即<100次/分、紫绀、肌张力低下;(2)除外早产儿原发性呼吸暂停;(3)有明确的原发病。
Neonatal apnea is a common emergency caused by certain diseases in the neonatal period, often indicating aggravation of the primary disease. If timely and reasonable treatment, the prognosis is very important. In our hospital from 1991 to 1996, a total of 30 cases were treated with scopolamine and aminophylline, with satisfactory results, are reported below. 1. Clinical data General information: 30 cases of children, 18 males and 12 females, age ≤ 5 days in 15 cases, 6 to 15 days in 13 cases, 16 to 28 days in 2 cases. Gestational age were 37 to 40 weeks, birth weight less than 2,500 grams in 5 cases. Primary disease: 15 cases of neonatal pneumonia, neonatal intracranial hemorrhage in 5 cases, 5 cases of neonatal sepsis, neonatal hypocalcemia in 3 cases, 2 cases of neonatal sclerema. Apnea with dyspnea in 16 cases, with convulsions in 22 cases. Apnea at least 3 episodes of attack, up to more than 40 times. Apnea duration lasts up to 50 hours. Diagnostic criteria: (1) respiratory arrest for less than 20 seconds accompanied by heart rate <100 beats / min, cyanotic, hypotonia; (2) except for premature children with primary apnea; (3) clear primary disease.