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本文研究28例急性胰腺炎血浆GAS与SP水平。结果:轻症者(n=18)GAS显著低于重症者(n=6),中位数(M)四分位间距(Q)分别为<50,<50～51对58,<50～74ng/L。P<0.05。GAS≤50和>50组的血淀酶分别为718±528(X±SD)和3773±3045,P<0.01。两组尿淀粉酶比较,前者M=1600,Q=1193～2022,后者M=3307,Q=1540～6150,P=0.07。疼痛剧烈者SP显著低于可忍受者(387.9±127.7对550.7±228.2ng/L,P<0.05),但在压痛局限或弥漫者间,反跳痛阴性、局限或弥漫者间,SP水平均无显著差别,轻重症间亦无显著差别。提示胃泌素可能刺激胰酶分泌从而加重病情,P物质可减轻疼痛,但和病情轻重无关。
In this paper, 28 cases of acute pancreatitis plasma GAS and SP levels. Results: The GAS of mild type (n = 18) was significantly lower than that of severe type (n = 6), and the median (M) quartile spacing (Q) was <50, 74ng / L. P <0.05. Blood amylase in GAS ≤50 and> 50 groups was 718 ± 528 (X ± SD) and 3773 ± 3045, respectively, P <0.01. The two groups of urine amylase comparison, the former M = 1600, Q = 1193 ~ 2022, the latter M = 3307, Q = 1540 ~ 6150, P = 0.07. SP in patients with severe pain was significantly lower than those in patients who were tolerated (387.9 ± 127.7 versus 550.7 ± 228.2 ng / L, P <0.05), but SP was significantly lower in those with or without tender pain, No significant difference, no significant difference between light and severe. Prompt gastrin may stimulate pancreatic secretion thereby aggravating the disease, substance P can reduce pain, but has nothing to do with the severity.