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为了研究长期连续性不卧床腹膜透析(CAPD)尿毒症患血浆中血管活性激素,即心钠素(ANP)、血浆肾素活性(PRA)和内皮素(ET)的改变,作者选择了17例尿素症病人,年龄13～65岁,平均38.5岁CAPD均在12周以上,尿毒症病因中,慢性肾小球肾炎14例,狼疮性肾炎1例,多囊肾1例和糖尿病肾病1例。这些病人临床上均无心衰表现。每日液体摄人量限制在1000～1500ml,尿量150～600ml。实验研究期间,分别在开始、第六周及第十二周采集静脉血标本,彩放免测定法,分别测定其血中血管活性激素的浓度。实验结束阶段,对上述每位末期直径及射血分数。实验结果及讨论:17例病人血浆中ANP、
In order to investigate the changes of plasma levels of vasoactive hormones, namely, atrial natriuretic peptide (ANP), plasma renin activity (PRA) and endothelin (ET), in patients with chronic continuous ambulatory peritoneal dialysis (CAPD) Uremia patients, aged 13 to 65 years, with an average of 38.5 years of CAPD were more than 12 weeks in the cause of uremia, chronic glomerulonephritis in 14 cases, 1 cases of lupus nephritis, 1 cases of polycystic kidney disease and diabetic nephropathy in 1 case. These patients are clinically no heart failure performance. Daily intake of liquid limited to 1000 ~ 1500ml, urine output 150 ~ 600ml. During the experimental study, venous blood samples were collected at the beginning, the sixth week and the twelfth week respectively, and the colorimetric immunoassay was used to determine the concentration of vasoactive hormone in blood. The end of the experiment, each of the above-mentioned end of the diameter and ejection fraction. Experimental results and discussion: 17 patients with plasma ANP,