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目的:探讨奥美拉唑与西米替丁治疗应激性胃溃疡的临床效果。方法:选取120例应激性胃溃疡患者作为本次研究对象,将其随机法分为两组,对照组60例患者采用西米替丁治疗,观察组60例采用奥美拉唑治疗,观察两组患者的治疗效果以及止血时间、胃液PH值、胃粘膜内PH值、静脉血胃泌素水平。结果:观察组的临床治疗总有效率明显高于对照组,有统计学意义(P<0.05)。观察组的止血时间短于对照组,观察组治疗后的胃液PH值、胃粘膜内PH值、静脉血胃泌素水平的改善情况均优于对照组,差异具有统计学意义(P<0.05)。结论:采用奥美拉唑治疗应激性胃溃疡效果显著优于西米替丁,可提高患者的生存质量,值得临床推广。
Objective: To investigate the clinical effects of omeprazole and cimetidine in the treatment of stress ulcer. Methods: 120 patients with stress ulcer were selected as the study subjects. The patients were randomly divided into two groups. 60 patients in the control group were treated with cimetidine, and 60 patients in the observation group were treated with omeprazole. Two groups of patients with treatment and bleeding time, gastric juice PH value, gastric mucosal PH value, venous blood gastrin levels. Results: The total effective rate of clinical observation in observation group was significantly higher than that in control group (P <0.05). The bleeding time in the observation group was shorter than that in the control group. The improvement of gastric mucosal pH value, gastric mucosal pH value and venous blood gastrin level in the observation group was better than that in the control group, with significant difference (P <0.05) . Conclusion: Omeprazole treatment of stress ulcer was significantly better than cimetidine, can improve the quality of life of patients, it is worth clinical promotion.