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将受试的近百名火法冶炼镍的作业人员分成补硒（１２５μｇ／ｄ）和补硒对照组，分别在补硒前、补硒半年及一年后测定外周血ＷＢＣ总数、分类、非特异酯酶阳性（ＡＮＡＥ￣＋）细胞％、Ｔ淋巴细胞ＣＤ及其亚群ＣＤ、ＣＤ及ＣＤ／ＣＤ比值。与补硒前比，补硒后一年ＡＮＡＥ￣＋％由７９．０±８．０上升到８４．０±４．０％，ＣＤ由６５．０±１０．０升高到７４．０±５．０％，ＣＤ由３４．０±６．０降至２７．０±５．０％，ＣＤ／ＣＤ比值由１．６±０．６增高到２．１±０．３。补硒一年后与相应的补硒对照组比，上述指标有改善或恢复。提示补硒对继续从事镍作业人员的Ｔ细胞％降低有回升的效果。对Ｔ淋巴细胞亚群ＣＤ和ＣＤ／ＣＤ比值的增减也有调节作用，使其亚群组成比例趋于正常。补硒对Ｔ淋巴细胞％变化的调节作用可能与它抗脂质过氧化作用有关。
Nearly one hundred pyrolyzed nickel workers were divided into selenium-enriched (125μg / d) and selenium-enriched control group, and the total number of WBC in peripheral blood was determined before selenium supplementing, selenium supplementing for half year and one year later, Esterase positive (ANAE ~ +) cells%, T lymphocyte CD and its subsets CD, CD and CD / CD ratio. Compared with pre-selenium, the percent of ANAE + increased from 79.0 ± 8.0 to 84.0 ± 4.0% one year after selenium supplementation, while the CD increased from 65.0 ± 10.0 to 74.0 ± 5.0%, CD decreased from 34.0 ± 6.0 to 27.0 ± 5.0%, and CD / CD increased from 1.6 ± 0.6 to 2.1 ± 0.3. One year after selenium supplementation with the corresponding selenium control group, the above indicators have improved or restored. Tip Selenium continue to engage in nickel workers to reduce the percentage of T cells have a rebound effect. T lymphocyte subsets CD and CD / CD ratio increases or decreases also regulate the proportion of its sub-group tends to be normal. The regulatory effect of selenium on% T lymphocytes may be related to its anti-lipid peroxidation.