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血管内皮细胞在人体多种生理和病理过程中发挥重要作用,一直以来都是研究的热点。其中使用最广泛的当属人脐静脉内皮细胞,然而就其各种亚系细胞有何特点和优劣,国内尚未见报道。现通过总结原代人脐静脉内皮细胞、延长寿命的脐静脉内皮细胞系、永生化的脐静脉内皮细胞系等在医学研究领域的应用和进展,对不同种类之间优势和局限性进行比较,从而更好地指导实际运用。
Vascular endothelial cells in the human body a variety of physiological and pathological processes play an important role, has been a research hotspot. One of the most widely used as a human umbilical vein endothelial cells, however, its characteristics of various subtypes of cells and merits, has not been reported in China. By summarizing the application and progress of primary human umbilical vein endothelial cells, extending the lifespan of umbilical vein endothelial cell lines and immortalized umbilical vein endothelial cell lines in the field of medical research, the advantages and limitations between different types are compared, To better guide the practical application.