疏血通联合奥扎格雷钠治疗急性脑梗塞随机平行对照研究

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[目的]观察疏血通联合奥扎格雷钠治疗急性脑梗塞疗效。[方法]使用随机平行对照方法,将180例住院患者按病志号抽签方法简单随机分为两组。对照组90例奥扎格雷钠80mg+0.9%氯化钠500m L,1次/d,静滴。治疗组90例疏血通6m L+0.9%氯化钠250m L,1次/d,静滴;奥扎格雷钠治疗同对照组。连续治疗2周为1疗程。观测临床症状、NDS评分、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈24例,显效25例,有效23例,无效8例,总有效率91.11%。对照组痊愈17例,显效25例,有效28例,无效20例,总有效率77.78%。治疗组疗效优于对照组(P<0.05)。NDS评分改善治疗组优于对照组(P<0.05)。[结论]疏血通联合奥扎格雷钠治疗急性脑梗塞,疗效满意,无严重不良反应,值得推广。 [Objective] To observe the curative effect of Shuxuetong combined with ozagrel sodium on acute cerebral infarction. [Methods] Using randomized parallel control method, 180 inpatients were randomly divided into two groups randomly according to the method of lot drawing of disease symbols. The control group 90 cases of ozagrel 80mg + 0.9% sodium chloride 500m L, 1 times / d, intravenous infusion. The treatment group, 90 cases of Shuxuetong 6m L + 0.9% sodium chloride 250m L, 1 times / d, intravenous infusion; ozagrel sodium treatment with the control group. Continuous treatment for 2 weeks for a course of treatment. Observed clinical symptoms, NDS score, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Results] The treatment group was cured in 24 cases, markedly effective in 25 cases, effective in 23 cases, ineffective in 8 cases, the total effective rate was 91.11%. The control group cured 17 cases, 25 cases markedly effective in 28 cases, 20 cases ineffective, the total effective rate 77.78%. The treatment group was better than the control group (P <0.05). NDS score improvement treatment group than the control group (P <0.05). [Conclusion] Shuxuetong combined with ozagrel sodium in the treatment of acute cerebral infarction has satisfactory curative effect and no serious adverse reactions and is worth popularizing.
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