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判断节段性肠炎和溃疡性结肠炎是否具有活动性,常有很大困难。作者等认为粪便α_1抗胰蛋白酶(下简称α_1AT)含量为这项诊断的一个可靠指标。作者等共对30例节段性肠炎和10例溃疡性结肠炎进行上述测定。此外,作为对照,又对这类患者进行其他检查如血红蛋白、血沉、血清C反应蛋白、血清白蛋白、血清α_1AT以及粪便铬~(51)标记白蛋白含量等。测定结果发现粪便中α_1AT含量和粪便铬~(51)标记白蛋白含量、Best指数、Talstadt指数以及血清白蛋白值有密切相互关系,而和血红蛋白、血沉、血清C反应蛋白以及血清α_1AT含量无关。6例患者在治疗停止后不久呈现复发。在复发前,当其他指标如Tals-tadt指数尚未出现变化时,粪便中α_1AT含量即已增高。最后作者等结论,粪便α_1AT清除量测定为一简
It is often very difficult to determine whether Crohn’s disease and colitis are active. The authors believe that stool α_1 antitrypsin (hereinafter referred to as α_1AT) content for the diagnosis of a reliable indicator. The authors of a total of 30 cases of colitis and 10 cases of ulcerative colitis the above determination. In addition, other tests such as hemoglobin, erythrocyte sedimentation rate, serum C-reactive protein, serum albumin, serum alpha-1 AT and stool chrome-51 labeled albumin were also taken as control. The results showed that there was a close relationship between α_1AT content in feces and chromium (51) labeled albumin content, Best index, Talstadt index and serum albumin value, but not hemoglobin, erythrocyte sedimentation rate, serum C - reactive protein and serum. Six patients relapsed shortly after the treatment was stopped. Before relapse, the level of α_1AT in feces was increased when the other indices such as the Tals-tadt index had not changed. The final author concluded that the excretion of α_1AT was measured as a simple cut