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目的:对一氧化碳中毒迟发性脑病(DEACMP)临床表现及危险因素进行分析,提出治疗方案。方法:从病例库抽取2014年12月至2015年12月,在黔南州人民医院接受急诊治疗的40例患者资料,对一氧化碳中毒迟发性脑病临床表现及潜在危险因素进行分析。本次40例一氧化碳(CO)中毒患者实施头颅CT或MRI诊断,结合是否出现广泛性脑白质损害为标准,确诊病况。对确诊者采用分期治疗方式,从急性期、康复期两个阶段执行针对性治疗方案。6个月后回访调查,统计治疗后患者的康复效果。结果:DEACMP是由于一氧化碳中毒患者在抢救过程中或症状恢复后,30 d内出现急性痴呆所致的精神疾病,以反应迟钝、智能低下、四肢肌张力增高、大小便失禁、昏迷等为表现,属于中毒治疗后假愈期的危险性病症。经过针对性治疗,本次40例均有效,有效率100%,无死亡,说明了病情分析对治疗的指导作用。结论:CO中毒患者救治易发生DEACMP,结合临床表现特征分析,必须及时对患者提供针对性治疗,确保生命安全。
Objective: To analyze the clinical manifestations and risk factors of delayed carbon monoxide poisoning encephalopathy (DEACMP) and propose the treatment plan. Methods: From December 2014 to December 2015, 40 cases of patients with emergency treatment in Qiannan People’s Hospital were collected from the case database to analyze the clinical manifestations and potential risk factors of delayed encephalopathy after carbon monoxide poisoning. The 40 cases of carbon monoxide poisoning patients with head CT or MRI diagnosis, combined with the occurrence of extensive white matter damage as the standard diagnosis of the disease. On the diagnosis of staged treatment, from the acute phase, the rehabilitation phase of the implementation of targeted treatment programs. Six months after the visit survey, the statistical treatment of patients after the rehabilitation effect. Results: DEACMP is a mental illness caused by acute dementia within 30 days after salvage or symptom recovery in patients with carbon monoxide poisoning. It is characterized by unresponsiveness, mental retardation, increased muscle tone of the extremities, incontinence and coma, Belonging to the treatment of poisoning after treatment of the risk of illness. After targeted treatment, the 40 cases were effective, effective rate of 100%, no death, indicating the guidance of the disease analysis of the treatment. Conclusion: The treatment of CO poisoning is prone to occur DEACMP, combined with the analysis of clinical manifestations, we must provide targeted treatment to patients in time to ensure the safety of life.