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通常以免疫应答(如接种后血清阳转率和抗体几何平均滴度)来评价麻疹疫苗的效果。世界卫生组织推荐血凝抑制(HI)、蚀斑减少中和(PRN)及酶联免疫吸附试验(ELISA)来检测血清样本中抗体水平(免疫后抗体滴度≥100mIU/ml为有保护水平)。上述三种方法的主要缺点是需在接种前后采
The effect of a measles vaccine is usually evaluated in terms of the immune response (such as the seroconversion rate after vaccination and the geometric mean antibody titer). WHO recommends hemagglutination inhibition (HI), plaque reduction neutralization (PRN) and enzyme-linked immunosorbent assay (ELISA) to detect antibody levels in serum samples (antibody titer ≥100 mIU / ml for protection) . The main disadvantage of these three methods is the need to pick before and after vaccination