论文部分内容阅读
目的:观察天花粉蛋白注射液治疗异位妊娠的有效性和安全性。方法:300例异位妊娠随机分为研究组和对照组各150例。研究组采用天花粉蛋白注射液治疗,对照组采用甲氨蝶呤配伍米非司酮治疗,观察比较2组治疗成功率和副反应。结果:研究组治疗成功123例,成功率82%,对照组治疗成功121例,成功率80.6%,2组成功率比较差异无统计学意义(P>0.05)。对照组和研究组患者经过治疗后,患者体内的β-HCG和孕酮都出现了明显的下降,差异有统计学意义(P<0.05),但研究组的下降水平要优于对照组,2组之间的差异较大,具有统计学意义(P<0.05),研究组患者发生副反应的几率低于对照组,2组之间的差异较为显著,有统计学意义(P<0.05)。结论:天花粉蛋白注射液能有效治疗异位妊娠,副反应较少。
Objective: To observe the efficacy and safety of trichosanthin injection in the treatment of ectopic pregnancy. Methods: 300 cases of ectopic pregnancy were randomly divided into study group and control group of 150 cases. The study group was treated with trichosanthin injection, while the control group was treated with methotrexate and mifepristone. The treatment success rate and side effects were compared between the two groups. Results: 123 cases were successfully treated in the study group, with a success rate of 82% and 121 cases successfully treated in the control group with a success rate of 80.6%. There was no significant difference in the success rates between the two groups (P> 0.05). After treatment, the levels of β-HCG and progesterone in the control group and the study group decreased significantly (P <0.05), but the decrease in the study group was superior to that in the control group. 2 The difference between the two groups was statistically significant (P <0.05). The incidence of side effects in the study group was lower than that in the control group. The difference between the two groups was significant (P <0.05). Conclusion: Trichosanthin injection can effectively treat ectopic pregnancy with fewer side effects.