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转化糖的比旋度及由此衍生的浓度折算因数,是与转化糖质量控制有关的两个重要的理化数据。国内某些资料在介绍这些数据时,有明显的错误,值得提出商榷,以求改正。首先,关于转化糖的比旋度,在南京药学院1959年编印的《有机化学》(11～15页)及燃料化学工业出版社1969年出版的《化工辞典》(274页)都介绍是-40.5°;而1977年由北京隆福医院等六个单位编写的《大输液》(119页).介绍是-38.5～-40.0°,并说明是由果糖比旋度与葡萄糖比旋度相减而得的,即91-52.5～93-53。我们发现,这些介绍均与理论推算及实际考察大不相符。其次,在关于转化糖注射液含量测定方面,从顾学裘教
The specific rotation of invert sugar and the concentration conversion factor derived therefrom are two important physical and chemical data related to the quality control of invert sugar. Certain information in the domestic introduction of these data, there are obvious errors, it is worth discussing in order to correct. First of all, about the specific rotation of invert sugar, “Organic Chemistry” (11-15 pages) edited by Nanjing Pharmaceutical College in 1959 and “Chemical Dictionary” (274 pages) published by Fuel Chemical Industry Press in 1969 are introduced -40.5 °; and in 1977 by the Beijing Longfu Hospital and other six units prepared “infusion” (119 pages). Introduction is -38.5 ~ -40.0 °, and shows that the ratio of specific rotation of glucose and glucose specific rotation Subtracted and obtained, that is 91-52.5 ~ 93-53. We find that these descriptions are not consistent with the theoretical calculation and actual investigation. Second, in terms of the content of invert sugar injection, Gu Qiu teach from Gu