弥漫性血管内凝血

• 作 者: 张庆慈
• 出 处: 云南中医学院学报
• 发表日期: 1980年02期
• 关键词: 血小板凝聚 微循环障碍 血管内溶血 微血栓形成 纤维蛋白沉积 内皮细胞 凝血活酶 凝血系统 致病因子 凝血因子

弥漫性血管内凝血(Disseminated In—travascular Coagulation简称DIC)是一个病理过程。由于某些致病因子的影响,在微循环内(主要是毛细血管和微静脉)发生广泛的纤维蛋白沉积和血小板凝聚,亦即在微循环内有广泛的微血栓形成。由此而引起一系列病理生理改变如凝血因子和血小板的消耗、广泛出血、继发性纤维蛋白溶解、微血管内溶血、组织坏死等,使有关脏器发生功能障碍与器质性改变。DIC可以在许多疾病过程中发生,且多十分危重,所以越来越受到临床医师的重视。要对DIC进行有效的防治就必须对它发生的机制加以认识,这就必

Disseminated Intravascular Coagulation (DIC) is a pathological process. Due to the influence of certain pathogenic factors, extensive fibrin deposition and platelet aggregation occur in the microcirculation (mainly in capillaries and venules), that is, there are extensive microthrombosis in the microcirculation. This caused a series of pathophysiological changes such as the consumption of clotting factors and platelets, extensive bleeding, secondary fibrinolysis, microvascular hemolysis, tissue necrosis, etc., causing dysfunction and organic changes in the relevant organs. DIC can occur in many diseases and is very critical. Therefore, clinicians pay more and more attention to it. To effectively prevent and control DIC, we must understand the mechanism of its occurrence. This must be