~(201)铊定量的单光子断层显像检测和定位冠心病:一个新技术的最优化和预期证实

来源 :国外医学.心血管疾病分册 | 被引量 : 0次 | 上传用户:liaodoctor
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~(201)铊心肌灌注平面(Planar)显像现已广泛用于衡量冠心病变程度,但常由于心肌区域正常和异常灌注影像的重叠而限制其对灌注缺损的检测、定位和确定大小。单光子断层显像(SPECT)具有较高的对比分辨和克服平面显像上述的局限性,并发展为定量有关~(201)铊在心肌中的三维分布的方法。本文旨在方法学上加以优化,并评价用优化的方法对冠心病的探测和分支确定冠状动脉病变的正确性。在183例~(201)以铊运动试验和静息再分布的SPECT 显像中对45例试点组和138例前瞻性研究组进行比较。试点组包括正常人20例和冠心病25例、正常的20例是以年龄、性别、症状以及运动试验心电图用 Bavesian 分析法为<5%冠心病可能者,冠心病25例是以血管造影中冠状动脉主干或分支狭窄≥ ~ (201) Thalar myocardial perfusion imaging (Planar) has been widely used to measure the degree of coronary heart disease, but often due to the overlap of normal and abnormal myocardial perfusion images to limit its detection of perfusion defects, location and size. Single-photon tomography (SPECT) has high contrast resolution and overcomes the above limitations of planar imaging and has been developed to quantify the three-dimensional distribution of ~ (201) thallium in the myocardium. This paper aims to optimize methodology and evaluate the correctness of coronary artery disease detection and branching by using an optimized approach. In 183 patients with ~ (201) SPECT scintigraphy with Thallium locomotion and resting redistribution, 45 pilot and 138 prospective study groups were compared. Pilot group included 20 cases of normal and 25 cases of coronary heart disease, the normal 20 cases based on age, gender, symptoms and exercise test ECG by Bavesian analysis was 5% of patients with coronary heart disease, 25 cases of coronary heart disease in angiography Coronary artery or branch stenosis ≥
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