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采用系列强度的刺激闪光记录20例30只正常眼的暗适应视网膜电图(ERG),应用频谱分析方法,探讨ERGa波的光强-反应函数。结果表明,在约2个对数单位范围,ERGa波为双谷a波,系振荡电位第1子波(OP_1)叠加于a波所致。临床测量双谷a波ERG时,先用频谱分析方法消除OP_1对a的分割,测量单谷a波的峰时和振幅。暗适应ERGa波的光强-反应关系曲线为“S”型,符合Naka-Rushton等式:R/Rmax=I ̄n(I ̄n+K ̄n),其中有三个独立参数:Rmax,K,n。
A series of dark adaptation electroretinograms (ERGs) of 30 normal eyes were recorded by using a series of intensity stimuli flash. Spectral analysis was used to investigate the intensity-response function of ERGa waves. The results show that the ERGa wave is a double-valley a-wave in the range of about two logarithmic units, and the first sub-wave of the oscillating potential (OP_1) is superimposed on the a-wave. When measuring the ERG of atrioventricular tachyarrhythmias, the spectral analysis method should be used to eliminate the segmentation of OP_1 and measure the peak time and the amplitude of a-wave a-wave. The dark-adapted ERGa wave has an intensity-response curve of type “S” according to the Naka-Rushton equation: R / Rmax = I¯n (I¯n + K¯n) with three independent parameters: Rmax, K, n .