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目的：探讨心脏瓣膜置换术后人工瓣功能异常经胸超声心动图的应用。方法选取2015年1月至2016年1月心胸外科行心脏瓣膜置换术的患者70例，均经超声心动图以及心血管造影明确诊断。70例患者按照数字统计双盲法分为两组。对照组30例采用二维多普勒超声检查，实验组40例采取人工瓣膜功能负荷试验及三维超声心动图检查。比较两组受检者峰值流速、跨瓣压差、有效瓣口面积。结果实验组峰值流速均值为（3.98±0.65）m/ s，跨瓣压差为（18.96±2.13）mmHg（1 mmHg =0.133 kPa），实验组高于对照组，差异有统计学意义（P <0.05）；实验组有效瓣口面积为（0.83±0.16）cm2，明显低于对照组，差异有统计学意义（P <0.05）。结论心脏瓣膜置换术后人工瓣功能异常可经人工瓣膜功能负荷试验及三维超声心动图检查的方式取得确切效果，对人工瓣膜的评价较传统二维超声更加全面，值得临床推广应用。“,”Objective To investigate the application of transthoracic echocardiography in artificial heart dysfunction after car-diac valve replacement. Methods From Jan. 2015 to Jan. 2016,70 heart valve replacement patients was selected,and all of them were diagnosed by echocardiography and angiography preoperative. Patients were divided into the two groups according to statistics,double-blind method,the control group(30 cases)was treated by two dimensional doppler ultrasonic inspection,the experiment group(40 cases)was given artificial valve function test and three-dimensional echocardiography for inspection. Peak systolic velocity,transvalvular gradients and effective mitral valve area in the two groups were compared. Results Peak systolic velocity in the experiment group was(3. 98 ± 0. 65)m/ s,transvalvular gradients was(18. 96 ± 2. 13)mmHg(1 mmHg =0. 133 kPa),which were higher than those in the control group,the differences were significant(P < 0. 05). Effective mitral valve area in the experiment group was(0. 83 ± 0. 16)cm2 ,which was lower than that in the control group,the difference was significant(P < 0. 05). Conclusion Artificial valve dysfunction after cardiac valve replacement by using manual valve function test and three-dimensional echocardiography way to achieve the exact effect,evaluation of artificial valve more comprehensive than traditional two-dimensional ultrasound,thus is worth the clinical application.